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Drug Resistance Patterns of Recombinant Herpes Simplex Virus DNA Polymerase Mutants Generated with a Set of Overlapping Cosmids and Plasmids

Herpes simplex virus (HSV) DNA polymerase (Pol) mutations can confer resistance to all currently available antiherpetic drugs. However, discrimination between mutations responsible for drug resistance and those that are part of viral polymorphism can be difficult with current methodologies. A new sy...

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Autores principales: Bestman-Smith, Julie, Boivin, Guy
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC161916/
https://ncbi.nlm.nih.gov/pubmed/12829822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7820-7829.2003
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