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Drug Resistance Patterns of Recombinant Herpes Simplex Virus DNA Polymerase Mutants Generated with a Set of Overlapping Cosmids and Plasmids
Herpes simplex virus (HSV) DNA polymerase (Pol) mutations can confer resistance to all currently available antiherpetic drugs. However, discrimination between mutations responsible for drug resistance and those that are part of viral polymorphism can be difficult with current methodologies. A new sy...
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| Formato: | Artigo |
| Idioma: | Inglês |
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American Society for Microbiology
2003
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161916/ https://ncbi.nlm.nih.gov/pubmed/12829822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7820-7829.2003 |
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