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Drug Resistance Patterns of Recombinant Herpes Simplex Virus DNA Polymerase Mutants Generated with a Set of Overlapping Cosmids and Plasmids

Herpes simplex virus (HSV) DNA polymerase (Pol) mutations can confer resistance to all currently available antiherpetic drugs. However, discrimination between mutations responsible for drug resistance and those that are part of viral polymorphism can be difficult with current methodologies. A new sy...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Bestman-Smith, Julie, Boivin, Guy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161916/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12829822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.14.7820-7829.2003
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