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Multiple eIF4GI-Specific Protease Activities Present in Uninfected and Poliovirus-Infected Cells

Cleavage of eukaryotic translation initiation factor 4GI (eIF4GI) is required for shutoff of host cell translation during poliovirus (PV) infection of HeLa cells. Reports published by several groups have led to confusion whether this cleavage is mediated by viral 2A protease (2A(pro)) or a putative...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zamora, Miguel, Marissen, Wilfred E., Lloyd, Richard E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135685/
https://ncbi.nlm.nih.gov/pubmed/11739682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.165-177.2002
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