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The Eukaryotic Translation Initiation Factor 4GI Is Cleaved by Different Retroviral Proteases

The initiation factor eIF4G plays a central role in the regulation of translation. In picornaviruses, as well as in human immunodeficiency virus type 1 (HIV-1), cleavage of eIF4G by the viral protease leads to inhibition of protein synthesis directed by capped cellular mRNAs. In the present work, cl...

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Hlavní autoři: Álvarez, Enrique, Menéndez-Arias, Luis, Carrasco, Luis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC262572/
https://ncbi.nlm.nih.gov/pubmed/14610163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12392-12400.2003
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