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Multiple eIF4GI-Specific Protease Activities Present in Uninfected and Poliovirus-Infected Cells

Cleavage of eukaryotic translation initiation factor 4GI (eIF4GI) is required for shutoff of host cell translation during poliovirus (PV) infection of HeLa cells. Reports published by several groups have led to confusion whether this cleavage is mediated by viral 2A protease (2A(pro)) or a putative...

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Detalhes bibliográficos
Main Authors: Zamora, Miguel, Marissen, Wilfred E., Lloyd, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135685/
https://ncbi.nlm.nih.gov/pubmed/11739682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.165-177.2002
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