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The SMN Complex Is Associated with snRNPs throughout Their Cytoplasmic Assembly Pathway

The common neurodegenerative disease spinal muscular atrophy is caused by reduced levels of the survival of motor neurons (SMN) protein. SMN associates with several proteins (Gemin2 to Gemin6) to form a large complex which is found both in the cytoplasm and in the nucleus. The SMN complex functions...

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Udgivet i:Mol Cell Biol
Principais autores: Massenet, Séverine, Pellizzoni, Livio, Paushkin, Sergey, Mattaj, Iain W., Dreyfuss, Gideon
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12192051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.18.6533-6541.2002
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