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The SMN Complex Is Associated with snRNPs throughout Their Cytoplasmic Assembly Pathway
The common neurodegenerative disease spinal muscular atrophy is caused by reduced levels of the survival of motor neurons (SMN) protein. SMN associates with several proteins (Gemin2 to Gemin6) to form a large complex which is found both in the cytoplasm and in the nucleus. The SMN complex functions...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135628/ https://ncbi.nlm.nih.gov/pubmed/12192051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6533-6541.2002 |
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