The SMN Complex Is Associated with snRNPs throughout Their Cytoplasmic Assembly Pathway

The common neurodegenerative disease spinal muscular atrophy is caused by reduced levels of the survival of motor neurons (SMN) protein. SMN associates with several proteins (Gemin2 to Gemin6) to form a large complex which is found both in the cytoplasm and in the nucleus. The SMN complex functions...

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Detalhes bibliográficos
Main Authors: Massenet, Séverine, Pellizzoni, Livio, Paushkin, Sergey, Mattaj, Iain W., Dreyfuss, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135628/
https://ncbi.nlm.nih.gov/pubmed/12192051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6533-6541.2002
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