The SMN Complex Is Associated with snRNPs throughout Their Cytoplasmic Assembly Pathway

The common neurodegenerative disease spinal muscular atrophy is caused by reduced levels of the survival of motor neurons (SMN) protein. SMN associates with several proteins (Gemin2 to Gemin6) to form a large complex which is found both in the cytoplasm and in the nucleus. The SMN complex functions...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Massenet, Séverine, Pellizzoni, Livio, Paushkin, Sergey, Mattaj, Iain W., Dreyfuss, Gideon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2002
Pynciau:
Gene Expression
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC135628/
https://ncbi.nlm.nih.gov/pubmed/12192051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6533-6541.2002
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