Membrane Phosphoinositides Control Insulin Secretion through their Effects on K(ATP) Channel Activity

ATP-sensitive potassium channels (K(ATP) channels) of pancreatic β-cells play key roles in glucose-stimulated insulin secretion by linking metabolic signals to cell excitability. Membrane phosphoinositides, in particular phosphatidylinositol 4,5-bisphosphates (PIP(2)), stimulate K(ATP) channels and...

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Hlavní autoři: Lin, Chia-Wei, Yan, Feifei, Shimamura, Satoko, Barg, Sebastian, Shyng, Show-Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350465/
https://ncbi.nlm.nih.gov/pubmed/16186385
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