Defective insulin secretion and enhanced insulin action in K(ATP) channel-deficient mice

ATP-sensitive K(+) (K(ATP)) channels regulate many cellular functions by linking cell metabolism to membrane potential. We have generated K(ATP) channel-deficient mice by genetic disruption of Kir6.2, which forms the K(+) ion-selective pore of the channel. The homozygous mice (Kir6.2(−/−)) lack K(AT...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Miki, Takashi, Nagashima, Kazuaki, Tashiro, Fumi, Kotake, Kazumi, Yoshitomi, Hideyuki, Tamamoto, Atsuko, Gonoi, Tohru, Iwanaga, Toshihiko, Miyazaki, Jun-ichi, Seino, Susumu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27906/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10402
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!