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Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide
The ATP-sensitive potassium (K(ATP)) channels in pancreatic β cells are critical in the regulation of glucose-induced insulin secretion. Although electrophysiological studies provide clues to the complex control of K(ATP) channels by ATP, MgADP, and pharmacological agents, the molecular mechanism of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15452/ https://ncbi.nlm.nih.gov/pubmed/9990013 |
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