Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide

The ATP-sensitive potassium (K(ATP)) channels in pancreatic β cells are critical in the regulation of glucose-induced insulin secretion. Although electrophysiological studies provide clues to the complex control of K(ATP) channels by ATP, MgADP, and pharmacological agents, the molecular mechanism of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ueda, Kazumitsu, Komine, Jun, Matsuo, Michinori, Seino, Susumu, Amachi, Teruo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1268
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