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Membrane Phosphoinositides Control Insulin Secretion through their Effects on K(ATP) Channel Activity
ATP-sensitive potassium channels (K(ATP) channels) of pancreatic β-cells play key roles in glucose-stimulated insulin secretion by linking metabolic signals to cell excitability. Membrane phosphoinositides, in particular phosphatidylinositol 4,5-bisphosphates (PIP(2)), stimulate K(ATP) channels and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1350465/ https://ncbi.nlm.nih.gov/pubmed/16186385 |
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