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Two peptide sequences can function cooperatively to facilitate binding and unfolding by ClpA and degradation by ClpAP
Clp/Hsp100 proteins comprise a large family of AAA(+) ATPases. Some Clp proteins function alone as molecular chaperones, whereas others act in conjunction with peptidases, forming ATP-dependent proteasome-like compartmentalized proteases. Protein degradation by Clp proteases is regulated primarily b...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1347992/ https://ncbi.nlm.nih.gov/pubmed/16410355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509154103 |
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