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Two peptide sequences can function cooperatively to facilitate binding and unfolding by ClpA and degradation by ClpAP

Clp/Hsp100 proteins comprise a large family of AAA(+) ATPases. Some Clp proteins function alone as molecular chaperones, whereas others act in conjunction with peptidases, forming ATP-dependent proteasome-like compartmentalized proteases. Protein degradation by Clp proteases is regulated primarily b...

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Autori principali: Hoskins, Joel R., Wickner, Sue
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347992/
https://ncbi.nlm.nih.gov/pubmed/16410355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509154103
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