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The Chinese Hamster Dihydrofolate Reductase Replication Origin Decision Point Follows Activation of Transcription and Suppresses Initiation of Replication within Transcription Units

Chinese hamster ovary (CHO) cells select specific replication origin sites within the dihydrofolate reductase (DHFR) locus at a discrete point during G(1) phase, the origin decision point (ODP). Origin selection is sensitive to transcription but not protein synthesis inhibitors, implicating a pretra...

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Bibliografiset tiedot
Päätekijät: Sasaki, Takayo, Ramanathan, Sunita, Okuno, Yukiko, Kumagai, Chiharu, Shaikh, Seemab S., Gilbert, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347040/
https://ncbi.nlm.nih.gov/pubmed/16428457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.1051-1062.2006
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