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Functional analysis of GC element binding and transcription in the hamster dihydrofolate reductase gene promoter.

Dihydrofolate reductase (DHFR) gene expression is required for cell growth. The DHFR gene promoter contains several GC elements capable of binding the transcription factor Sp1. In this report we have characterized the effect of protein(s) binding to these sequence elements in the Chinese hamster DHF...

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Autors principals: Swick, A G, Blake, M C, Kahn, J W, Azizkhan, J C
Format: Artigo
Idioma:Inglês
Publicat: 1989
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC335132/
https://ncbi.nlm.nih.gov/pubmed/2587257
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