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Perforin-Deficient CD8(+) T Cells Mediate Fatal Lymphocytic Choriomeningitis despite Impaired Cytokine Production
Intracerebral (i.c.) infection with lymphocytic choriomeningitis virus (LCMV) is one of the most studied models for virus-induced immunopathology, and based on results from perforin-deficient mice, it is currently assumed that fatal disease directly reflects perforin-mediated cell lysis. However, re...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346958/ https://ncbi.nlm.nih.gov/pubmed/16414999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1222-1230.2006 |
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