Differential Impact of Interferon Regulatory Factor 7 in Initiation of the Type I Interferon Response in the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System versus the Periphery

Interferon (IFN) regulatory factors (IRFs) are a family of transcription factors involved in regulating type I IFN genes and other genes participating in the early antiviral host response. To better understand the mechanisms involved in virus-induced central nervous system (CNS) inflammation, we stu...

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Detalhes bibliográficos
Main Authors: Christensen, Jeanette Erbo, Fenger, Christina, Issazadeh-Navikas, Shohreh, Krug, Anna, Liljestrøm, Peter, Goriely, Stanislas, Paludan, Søren Riis, Finsen, Bente, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416342/
https://ncbi.nlm.nih.gov/pubmed/22514347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07090-11
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