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Impaired Virus Control and Severe CD8(+) T-Cell-Mediated Immunopathology in Chimeric Mice Deficient in Gamma Interferon Receptor Expression on both Parenchymal and Hematopoietic Cells
Bone marrow chimeras were used to determine the cellular target(s) for the antiviral activity of gamma interferon (IFN-γ). By transfusing such mice with high numbers of naive virus-specific CD8(+) T cells, a system was created in which the majority of virus-specific CD8(+) T cells would be capable o...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1181549/ https://ncbi.nlm.nih.gov/pubmed/16014969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.10073-10076.2005 |
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