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Impaired Virus Control and Severe CD8(+) T-Cell-Mediated Immunopathology in Chimeric Mice Deficient in Gamma Interferon Receptor Expression on both Parenchymal and Hematopoietic Cells

Bone marrow chimeras were used to determine the cellular target(s) for the antiviral activity of gamma interferon (IFN-γ). By transfusing such mice with high numbers of naive virus-specific CD8(+) T cells, a system was created in which the majority of virus-specific CD8(+) T cells would be capable o...

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מידע ביבליוגרפי
Main Authors: Henrichsen, Pernille, Bartholdy, Christina, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181549/
https://ncbi.nlm.nih.gov/pubmed/16014969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.10073-10076.2005
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