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Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion
Studies in tissue culture cells have demonstrated a role for the Ras-like GTPase Rap1 in the regulation of integrin-mediated cell-matrix and cadherin-mediated cell-cell contacts. To analyze the function of Rap1 in vivo, we have disrupted the Rap1A gene by homologous recombination. Mice homozygous fo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346907/ https://ncbi.nlm.nih.gov/pubmed/16382154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.2.643-653.2006 |
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