Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity

BACKGROUND: Retrotransposition of mRNA transcripts gives occasionally rise to functional retrogenes. Through acquiring tempero-spatial expression patterns distinct from their parental genes and/or functional mutations in their coding sequences, such retrogenes may in principle reshape signalling net...

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Bibliographic Details
Main Authors: Zemojtel, Tomasz, Duchniewicz, Marlena, Zhang, Zhongchun, Paluch, Taisa, Luz, Hannes, Penzkofer, Tobias, Scheele, Jürgen S, Zwartkruis, Fried JT
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831893/
https://ncbi.nlm.nih.gov/pubmed/20170508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-55
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