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Modulation of Prion Formation, Aggregation, and Toxicity by the Actin Cytoskeleton in Yeast

Self-perpetuating protein aggregates transmit prion diseases in mammals and heritable traits in yeast. De novo prion formation can be induced by transient overproduction of the corresponding prion-forming protein or its prion domain. Here, we demonstrate that the yeast prion protein Sup35 interacts...

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Autores principales: Ganusova, Elena E., Ozolins, Laura N., Bhagat, Srishti, Newnam, Gary P., Wegrzyn, Renee D., Sherman, Michael Y., Chernoff, Yury O.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346895/
https://ncbi.nlm.nih.gov/pubmed/16382152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.2.617-629.2006
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