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Impact of Capsid Conformation and Rep-Capsid Interactions on Adeno-Associated Virus Type 2 Genome Packaging
Single-stranded genomes of adeno-associated virus (AAV) are packaged into preformed capsids. It has been proposed that packaging is initiated by interaction of genome-bound Rep proteins to the capsid, thereby targeting the genome to the portal of encapsidation. Here we describe a panel of mutants wi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346863/ https://ncbi.nlm.nih.gov/pubmed/16378983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.810-820.2006 |
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