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A Conformational Change in the Adeno-Associated Virus Type 2 Capsid Leads to the Exposure of Hidden VP1 N Termini

The complex infection process of parvoviruses is not well understood so far. An important role has been attributed to a phospholipase A(2) domain which is located within the unique N terminus of the capsid protein VP1. Based on the structural difference between adeno-associated virus type 2 wild-typ...

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Detalhes bibliográficos
Main Authors: Kronenberg, Stephanie, Böttcher, Bettina, von der Lieth, Claus W., Bleker, Svenja, Kleinschmidt, Jürgen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082756/
https://ncbi.nlm.nih.gov/pubmed/15827144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5296-5303.2005
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