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Pharmacodynamics of a New Streptogramin, XRP 2868, in Murine Thigh and Lung Infection Models
XRP 2868 is a new streptogramin antibiotic with broad-spectrum activity against gram-positive cocci. We used the neutropenic murine thigh and lung infection models to characterize the time course of antimicrobial activity of XRP 2868 and determine which pharmacokinetic/pharmacodynamic (PK/PD) parame...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346813/ https://ncbi.nlm.nih.gov/pubmed/16377693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.243-249.2006 |
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