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Pharmacodynamics of a New Cephalosporin, PPI-0903 (TAK-599), Active against Methicillin-Resistant Staphylococcus aureus in Murine Thigh and Lung Infection Models: Identification of an In Vivo Pharmacokinetic-Pharmacodynamic Target

PPI-0903 is a new cephalosporin with broad-spectrum activity, including beta-lactam-resistant Streptococcus pneumoniae and Staphylococcus aureus. We used the neutropenic murine thigh and lung infection models to examine the pharmacodynamic characteristics of PPI-0903. Serum drug levels following fou...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Andes, D., Craig, W. A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426945/
https://ncbi.nlm.nih.gov/pubmed/16569855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1376-1383.2006
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