Pharmacokinetic-Pharmacodynamic Modeling of the In Vitro Activities of Oxazolidinone Antimicrobial Agents against Methicillin-Resistant Staphylococcus aureus

Linezolid is the first FDA-approved oxazolidinone with activity against clinically important gram-positive pathogens, including methicillin (meticillin)-resistant Staphylococcus aureus (MRSA). RWJ-416457 is a new oxazolidinone with an antimicrobial spectrum similar to that of linezolid. The goal of...

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Autores principales: Schmidt, Stephan, Sabarinath, Sreedharan Nair, Barbour, April, Abbanat, Darren, Manitpisitkul, Prasarn, Sha, Sue, Derendorf, Hartmut
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786350/
https://ncbi.nlm.nih.gov/pubmed/19786607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00633-09
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