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Assessment of the Impact of Dosing Time on the Pharmacokinetics/Pharmacodynamics of Prednisolone
Prednisolone is widely used for the treatment of inflammation and auto-immune diseases. It exhibits nonlinear pharmacokinetics (PK); and its induced systemic effects (pharmacodynamics (PD)) are commonly evaluated with two biomarkers, cortisol and blood lymphocytes in plasma. Circadian patterns are o...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer US
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751388/ https://ncbi.nlm.nih.gov/pubmed/18581240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9038-3 |
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