In Vivo Efficacy of Ceftaroline (PPI-0903), a New Broad-Spectrum Cephalosporin, Compared with Linezolid and Vancomycin against Methicillin-Resistant and Vancomycin-Intermediate Staphylococcus aureus in a Rabbit Endocarditis Model

Using the rabbit endocarditis model, we compared the activity of a new broad-spectrum cephalosporin, ceftaroline, with those of linezolid and vancomycin against methicillin-resistant Staphylococcus aureus. After a 4-day treatment, ceftaroline exhibited superior bactericidal in vivo activity against...

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Detalhes bibliográficos
Main Authors: Jacqueline, Cédric, Caillon, Jocelyne, Le Mabecque, Virginie, Miègeville, Anne-Françoise, Hamel, Antoine, Bugnon, Denis, Ge, James Yigong, Potel, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043200/
https://ncbi.nlm.nih.gov/pubmed/17591849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01242-06
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