In Vivo Efficacy of Continuous Infusion versus Intermittent Dosing of Linezolid Compared to Vancomycin in a Methicillin-Resistant Staphylococcus aureus Rabbit Endocarditis Model

Linezolid is the first drug issued from the oxazolidinones, a novel class of antimicrobial agents with potent activity against gram-positive pathogens. A rabbit endocarditis model was used to compare the in vivo activities of different linezolid regimens mimicking intermittent dosing of 10 mg/kg of...

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Hlavní autoři: Jacqueline, Cédric, Batard, Eric, Perez, Lucia, Boutoille, David, Hamel, Antoine, Caillon, Jocelyne, Kergueris, Marie-France, Potel, Gilles, Bugnon, Denis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC132754/
https://ncbi.nlm.nih.gov/pubmed/12435665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3706-3711.2002
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