In Vivo Efficacy of Continuous Infusion versus Intermittent Dosing of Linezolid Compared to Vancomycin in a Methicillin-Resistant Staphylococcus aureus Rabbit Endocarditis Model

Linezolid is the first drug issued from the oxazolidinones, a novel class of antimicrobial agents with potent activity against gram-positive pathogens. A rabbit endocarditis model was used to compare the in vivo activities of different linezolid regimens mimicking intermittent dosing of 10 mg/kg of...

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Dettagli Bibliografici

Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Jacqueline, Cédric, Batard, Eric, Perez, Lucia, Boutoille, David, Hamel, Antoine, Caillon, Jocelyne, Kergueris, Marie-France, Potel, Gilles, Bugnon, Denis
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3706-3711.2002
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