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Pharmacodynamics of a New Streptogramin, XRP 2868, in Murine Thigh and Lung Infection Models

XRP 2868 is a new streptogramin antibiotic with broad-spectrum activity against gram-positive cocci. We used the neutropenic murine thigh and lung infection models to characterize the time course of antimicrobial activity of XRP 2868 and determine which pharmacokinetic/pharmacodynamic (PK/PD) parame...

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Detalhes bibliográficos
Main Authors: Andes, D., Craig, W. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346813/
https://ncbi.nlm.nih.gov/pubmed/16377693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.243-249.2006
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