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Engineered Biosynthesis of Aklanonic Acid Analogs

Aklanonic acid, an anthraquinone natural product, is a common advanced intermediate in the biosynthesis of several antitumor polyketide antibiotics, including doxorubicin and aclacinomycin A. Intensive semisynthetic and biosynthetic efforts have been directed toward developing improved analogs of th...

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Detalhes bibliográficos
Main Authors: Lee, Taek Soon, Khosla, Chaitan, Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1343498/
https://ncbi.nlm.nih.gov/pubmed/16131203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja051429z
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