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Challenges and opportunities for engineering assembly-line polyketide biosynthesis in Escherichia coli
Assembly-line polyketide synthases generate natural products that have led to many live-saving drugs. The use of E. coli as a heterologous host for reconstituting these enormous and complex enzymatic machines has and will continue to be a critical strategy for understanding them. Here, we concisely...
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| Pubblicato in: | Metab Eng Commun |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7283498/ https://ncbi.nlm.nih.gov/pubmed/32547924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mec.2019.e00106 |
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