Challenges and opportunities for engineering assembly-line polyketide biosynthesis in Escherichia coli

Assembly-line polyketide synthases generate natural products that have led to many live-saving drugs. The use of E. coli as a heterologous host for reconstituting these enormous and complex enzymatic machines has and will continue to be a critical strategy for understanding them. Here, we concisely...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Metab Eng Commun
Main Authors: Yuet, Kai P., Khosla, Chaitan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Special issue on The Natural Product Issue edited by Greg Stephanopoulos, Anthony Sinskey and Kang Zhou
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283498/
https://ncbi.nlm.nih.gov/pubmed/32547924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mec.2019.e00106
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker