Cytoplasmic Death Signal Triggered by Src-Mediated Phosphorylation of the Adenovirus E4orf4 Protein
In transformed cells, the adenovirus E4orf4 death factor works in part by inducing a Src-mediated cytoplasmic apoptotic signal leading to caspase-independent membrane blebbing and cell death. Here we show that Src-family kinases modulate E4orf4 phosphorylation on tyrosine residues. Mutation of tyros...
Spremljeno u:
| Izdano u: | Mol Cell Biol |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.1.41-56.2002 |
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