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Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.

The adenovirus type 5 243R E1A protein induces p53-dependent apoptosis in the absence of the 19- and 55-kDa E1B polypeptides. This effect appears to result from an accumulation of p53 protein and is unrelated to expression of E1B products. We now report that in the presence of the E1B 55-kDa polypep...

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Autors principals: Querido, E, Marcellus, R C, Lai, A, Charbonneau, R, Teodoro, J G, Ketner, G, Branton, P E
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC191529/
https://ncbi.nlm.nih.gov/pubmed/9094654
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