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Regulation of the Transcription Factor Gcn4 by Pho85 Cyclin Pcl5

The yeast transcription factor Gcn4 is regulated by amino acid starvation at the levels of both protein synthesis and stability. Gcn4 degradation depends on the ubiquitination complex SCF(CDC4) and requires phosphorylation by the cyclin-dependent kinase Pho85. Here, we show that Pcl5 is the Pho85 cy...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Shemer, Revital, Meimoun, Ariella, Holtzman, Tsvi, Kornitzer, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12101234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.15.5395-5404.2002
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