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Regulation of the Transcription Factor Gcn4 by Pho85 Cyclin Pcl5

The yeast transcription factor Gcn4 is regulated by amino acid starvation at the levels of both protein synthesis and stability. Gcn4 degradation depends on the ubiquitination complex SCF(CDC4) and requires phosphorylation by the cyclin-dependent kinase Pho85. Here, we show that Pcl5 is the Pho85 cy...

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Detalhes bibliográficos
Main Authors: Shemer, Revital, Meimoun, Ariella, Holtzman, Tsvi, Kornitzer, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133946/
https://ncbi.nlm.nih.gov/pubmed/12101234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5395-5404.2002
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