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Regulation of the Transcription Factor Gcn4 by Pho85 Cyclin Pcl5

The yeast transcription factor Gcn4 is regulated by amino acid starvation at the levels of both protein synthesis and stability. Gcn4 degradation depends on the ubiquitination complex SCF(CDC4) and requires phosphorylation by the cyclin-dependent kinase Pho85. Here, we show that Pcl5 is the Pho85 cy...

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Sonraí Bibleagrafaíochta
Main Authors: Shemer, Revital, Meimoun, Ariella, Holtzman, Tsvi, Kornitzer, Daniel
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133946/
https://ncbi.nlm.nih.gov/pubmed/12101234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5395-5404.2002
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