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Sim2 Mutants Have Developmental Defects Not Overlapping with Those of Sim1 Mutants

The mouse genome contains two Sim genes, Sim1 and Sim2. They are presumed to be important for central nervous system (CNS) development because they are homologous to the Drosophila single-minded (sim) gene, mutations in which cause a complete loss of CNS midline cells. In the mammalian CNS, Sim2 and...

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Detalhes bibliográficos
Main Authors: Goshu, Eleni, Jin, Hui, Fasnacht, Rachel, Sepenski, Mike, Michaud, Jacques L., Fan, Chen-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133848/
https://ncbi.nlm.nih.gov/pubmed/12024028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4147-4157.2002
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