Targeted Disruption of SPI3/Serpinb6 Does Not Result in Developmental or Growth Defects, Leukocyte Dysfunction, or Susceptibility to Stroke

Protease inhibitor 6 (PI-6/SERPINB6) is a widely expressed nucleocytoplasmic serpin. It inhibits granulocyte cathepsin G and neuronal neuropsin, and it is thought to protect cells from death caused by ectopic release or internalization of protease during stress such as infection or cerebral ischemia...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Scarff, Katrina L., Ung, Kheng S., Nandurkar, Harshal, Crack, Peter J., Bird, Catherina H., Bird, Phillip I.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.4075-4082.2004
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