Targeted Disruption of SPI3/Serpinb6 Does Not Result in Developmental or Growth Defects, Leukocyte Dysfunction, or Susceptibility to Stroke

Protease inhibitor 6 (PI-6/SERPINB6) is a widely expressed nucleocytoplasmic serpin. It inhibits granulocyte cathepsin G and neuronal neuropsin, and it is thought to protect cells from death caused by ectopic release or internalization of protease during stress such as infection or cerebral ischemia...

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Hlavní autoři: Scarff, Katrina L., Ung, Kheng S., Nandurkar, Harshal, Crack, Peter J., Bird, Catherina H., Bird, Phillip I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC387772/
https://ncbi.nlm.nih.gov/pubmed/15082799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.4075-4082.2004
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