Sim2 Mutants Have Developmental Defects Not Overlapping with Those of Sim1 Mutants

The mouse genome contains two Sim genes, Sim1 and Sim2. They are presumed to be important for central nervous system (CNS) development because they are homologous to the Drosophila single-minded (sim) gene, mutations in which cause a complete loss of CNS midline cells. In the mammalian CNS, Sim2 and...

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Hlavní autoři: Goshu, Eleni, Jin, Hui, Fasnacht, Rachel, Sepenski, Mike, Michaud, Jacques L., Fan, Chen-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC133848/
https://ncbi.nlm.nih.gov/pubmed/12024028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4147-4157.2002
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