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Sim2 Mutants Have Developmental Defects Not Overlapping with Those of Sim1 Mutants

The mouse genome contains two Sim genes, Sim1 and Sim2. They are presumed to be important for central nervous system (CNS) development because they are homologous to the Drosophila single-minded (sim) gene, mutations in which cause a complete loss of CNS midline cells. In the mammalian CNS, Sim2 and...

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Autors principals: Goshu, Eleni, Jin, Hui, Fasnacht, Rachel, Sepenski, Mike, Michaud, Jacques L., Fan, Chen-Ming
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC133848/
https://ncbi.nlm.nih.gov/pubmed/12024028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4147-4157.2002
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