Src Catalytic but Not Scaffolding Function Is Needed for Integrin-Regulated Tyrosine Phosphorylation, Cell Migration, and Cell Spreading

Src family kinases (SFKs) are crucial for signaling through a variety of cell surface receptors, including integrins. There is evidence that integrin activation induces focal adhesion kinase (FAK) autophosphorylation at Y397 and that Src binds to and is activated by FAK to carry out subsequent phosp...

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Hlavní autoři: Cary, Leslie A., Klinghoffer, Richard A., Sachsenmaier, Christoph, Cooper, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC133722/
https://ncbi.nlm.nih.gov/pubmed/11909938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2427-2440.2002
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