Src Catalytic but Not Scaffolding Function Is Needed for Integrin-Regulated Tyrosine Phosphorylation, Cell Migration, and Cell Spreading

Src family kinases (SFKs) are crucial for signaling through a variety of cell surface receptors, including integrins. There is evidence that integrin activation induces focal adhesion kinase (FAK) autophosphorylation at Y397 and that Src binds to and is activated by FAK to carry out subsequent phosp...

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Detalhes bibliográficos
Main Authors: Cary, Leslie A., Klinghoffer, Richard A., Sachsenmaier, Christoph, Cooper, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133722/
https://ncbi.nlm.nih.gov/pubmed/11909938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2427-2440.2002
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