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Src Phosphorylates Cas on Tyrosine 253 to Promote Migration of Transformed Cells

Cas is a member of the focal adhesion complex. Phosphorylation of Cas by Src is an important event leading to cell transformation. Using mass spectrometry, we have mapped 11 sites in Cas that are phosphorylated by Src. These sites are all located between residues 132 and 414 of Cas, in a region that...

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Detalhes bibliográficos
Main Authors: Goldberg, Gary S., Alexander, David B., Pellicena, Patricia, Zhang, Zhong-Yin, Tsudal, Hiroyuki, Miller, W. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441571/
https://ncbi.nlm.nih.gov/pubmed/12972425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M307526200
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