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Src Phosphorylates Cas on Tyrosine 253 to Promote Migration of Transformed Cells

Cas is a member of the focal adhesion complex. Phosphorylation of Cas by Src is an important event leading to cell transformation. Using mass spectrometry, we have mapped 11 sites in Cas that are phosphorylated by Src. These sites are all located between residues 132 and 414 of Cas, in a region that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goldberg, Gary S., Alexander, David B., Pellicena, Patricia, Zhang, Zhong-Yin, Tsudal, Hiroyuki, Miller, W. Todd
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441571/
https://ncbi.nlm.nih.gov/pubmed/12972425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M307526200
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