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Individual Cas Phosphorylation Sites Are Dispensable for Processive Phosphorylation by Src and Anchorage-independent Cell Growth

Cas is a multidomain signaling protein that resides in focal adhesions. Cas possesses a large central substrate domain containing 15 repeats of the sequence YXXP, which are phosphorylated by Src. The phosphorylation sites are essential for the roles of Cas in cell migration and in regulation of the...

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Detalhes bibliográficos
Main Authors: Patwardhan, Parag, Shen, Yongquan, Goldberg, Gary S., Miller, W. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441569/
https://ncbi.nlm.nih.gov/pubmed/16707485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602311200
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