Stimulation of DNA Synthesis Activity of Human DNA Polymerase κ by PCNA

Humans have three DNA polymerases, Polη, Polκ, and Polι, which are able to promote replication through DNA lesions. However, the mechanism by which these DNA polymerases are targeted to the replication machinery stalled at a lesion site has remained unknown. Here, we provide evidence for the physica...

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Main Authors: Haracska, Lajos, Unk, Ildiko, Johnson, Robert E., Phillips, Barbara B., Hurwitz, Jerard, Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133560/
https://ncbi.nlm.nih.gov/pubmed/11784855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.3.784-791.2002
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